Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy

June 2023 | New Publication
Braun F et al., J Clin Invest 2023
This study from the Laboratory for Renal Intercellular Communication via Extracellular Vesicles  reconceptualizes Fabry-associated cell injury beyond Gb3 accumulation, and introduces SNCA modulation as a potential intervention, especially for patients with Fabry nephropathy.
 

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JCI - Synuclein α accumulation mediates podocyte injury in Fabry nephropathy

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