Metabolic kidney diseases are contributing increasingly to global morbidity and mortality. Among them are obesity, hypertension and metabolic syndrome, leading to Diabetic Nephropathy or diabetes-independent kidney disease. Metabolic changes in the tissue lead among others to hyperfiltration, microalbuminuria and glomerular hypertrophy.

Single cell resolution of gene expression will provide a more detailed picture of the complex cellular interaction in disease for the development of novel targets for treatment and prevention of kidney disease. 

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