— Nicola Wanner, PhD
©Nicola Wanner
We are using epigenetic and transcriptional profiling, imaging and nanobodies to understand nephrology: From environmental stressors causing disruption in renal development and the impact of epigenetic regulation of nephrogenesis to investigating renal diseases such as glomerulonephritis and the interaction between the immune system and renal cells, we are exploring multiple facets of renal physiology and disease. As members of the CRC 1192, we use nanobody technology to develop novel treatment strategies for kidney diseases.
since 2020
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Junior group leader/Principal Investigator CRC 1192 Project B5 |
since 2017
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Laboratory head, III. Medical Department, University Medical Center Hamburg Eppendorf, Prof. Dr. T.B. Huber |
2004 - 2009
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Molecular Medicine at the Albert-Ludwigs University Freiburg im Breisgau, Germany |
2013 - 2017 | PhD at the University of Freiburg – Spemann Graduate School of Biology and Medicine (summa cum laude) |
2009 - 2017 | Diploma in Molecular Medicine at the University of Freiburg |
2013 - 2017 | Postdoctoral Fellow, Department of Nephrology, University Hospital Freiburg, Germany, Prof. Dr. Tobias B. Huber |
2024 |
Award of the UKE Foundation |
2014 - 2020
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Rainer-Greger Prize for PhD thesis in Nephrology |
2009 - 2013
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2009 - 2013 PhD Fellowship of the Spemann Graduate School of Biology and Medicine (SGBM) |
1. | ATP-Gated P2X7-Ion Channel on Kidney-Resident Natural Killer T Cells and Memory T Cells in Intrarenal Inflammation. |
2. | Adeno-associated virus-based gene therapy treats inflammatory kidney disease in mice. |
3. | Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens. |
4. | Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy |
5. | Molecular consequences of SARS-CoV-2 liver tropism. |
6. | Effects of Environmental Conditions on Nephron Number: Modeling Maternal Disease and Epigenetic Regulation in Renal Development. |
7. | Multiorgan and Renal Tropism of SARS-CoV-2. |
8. | mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans. |
9. | DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation. |
10. | Unraveling the role of podocyte turnover in glomerular aging and injury. |
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20246 Hamburg Germany