Abt

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  • Mailadresse: Jana Abt, MD
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  • Datum + Kategorie: Clinician Scientist

Dunay

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  • Mailadresse: Gabor Dunay, MD
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  • Datum + Kategorie: Clinician Scientist

Mühlig

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  • Mailadresse: Anne Mühlig, MD/PhD
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  • Datum + Kategorie: Post Doc

Anne Mühlig

Laboratory for Pediatric Nephrology Research

Mission Statement

“Uncover the molecular and sex-specific mechanisms underlying pediatric kidney diseases, to enable the development of precise, individualized therapies”

— Dr. med. Anne Mühlig

Team Members

Research

Our research group investigates the molecular mechanisms underlying the development and progression of pediatric kidney diseases. A particular focus lies on sex-specific differences and the identification and characterization of differentially regulated pathways.We are especially interested in the role of the immune system and its sex-specific regulation in disease processes. To address these questions, we combine established mouse models and cell culture systems with state-of-the-art omics technologies and standardized molecular biological methods. Our goal is to uncover novel molecular mechanisms and translate these findings into druggable targets, ultimately enabling the development of individualized therapies for children with kidney diseases.

Anne Mühlig, MD

Junior Group Leader

Department of Pediatrics, University Medical Center Hamburg-Eppendorf (UKE)
Martinistr. 52
20246 Hamburg, Germany

CV

  • Current Position

    since 2025
    		 Principal Investigator in CRC/TR 422 Project A4
    since 2024
    		 Principal Investigator in CRC1192 Project B8
    since 2011 Physician, Department of Pediatrics, University Medical Center Hamburg- Eppendorf

  • University Training

    2001 - 2007

    Study of Medicine, Medical University Innsbruck, Austria

  • Academic qualifications

    20152020

    Board Certification for Pediatrics

    20152020

    		 PhD-Thesis: Department of Pediatrics, University Medical Center Hamburg-Eppendorf, Germany
    2007

    MD Thesis: 
Department of Pediatrics, Medical University Innsbruck, Austria

  • Previous professional career

    Clinical postgraduate education:

    2011 - 2015

    Attending Physician for Pediatrics, University Medical Center Hamburg- Eppendorf, Germany
    2007 - 2011

    Attending Physician for Pediatrics, Medical University Innsbruck, Austria
     

  • Selected awards and honors

    2024 - 2020

    Grundlagen-Forschungspreis der Gesellschaft für Pädiatrische Nephrologie
    2023

    Dr. Martini Preis, University Medical Center Hamburg-Eppendorf

Selected publications

1.
Mühlig AK, Hengel FE, Oh J, Tomas NM, Huber TB. Pediatr Nephrol. 2026 Apr 23. doi: 10.1007/s00467-026-07292-9. 
2.
Liaukouskaya N, Hengel FE, Mühlig A, Tomas NM, Huber TB. Clin J Am Soc Nephrol. 2026 Jan 21. doi: 10.2215/CJN.0000001008. 
3.
Bruno V, Mühlig AK, Oh J, Licht C. Mol Cell Pediatr. 2023 Apr 15;10(1):3. 
4.
Hengel FE, Chong MCZ, Leung WY, Dehde S, Mühlig A, Janneck M, Wu HHL, Huber TB, Ponnusamy A, Tomas NM. Kidney Int Rep. 2025 May 12;10(8):2800-2804. 
5.
Gies SE, Hänzelmann S, Kylies D, Lassé M, Lagies S, Hausmann F, Khatri R, Zolotarev N, Poets M, Zhang T, Demir F, Billing AM, Quaas J, Meister E, Engesser J, Mühlig AK, Lu S, Liu S, Chilla S, Edenhofer I, Czogalla J, Braun F, Kammerer B, Puelles VG, Bonn S, Rinschen MM, Lindenmeyer M, Huber TB. Am J Physiol Renal Physiol. 2024 Nov 1;327(5):F822-F844. 
6.
Braun F, Abed A, Sellung D, Rogg M, Woidy M, Eikrem O, Wanner N, Gambardella J, Laufer SD, Haas F, Wong MN, Dumoulin B, Rischke P, Mühlig AK, Sachs W, von Cossel K, Schulz K, Muschol N, Gersting SW, Muntau AC, Kretz O, Hahn O, Rinschen MM, Mauer M, Bork T, Grahammer F, Liang W, Eierhoff T, Römer W, Hansen A, Meyer-Schwesinger C, Iaccarino G, Tøndel C, Marti HP, Najafian B, Puelles VG, Schell C, Huber TB.  J Clin Invest. 2023 Apr 4:e157782.
7.
Mühlig AK, Oh J, Huber TB.  Kidney Int. 2023 Mar;103(3):464-466. 
8.
Mühlig AK, Steingröver J, Heidelbach HS, Wingerath M, Sachs W, Hermans-Borgmeyer I, Meyer-Schwesinger C, Choi HY, Lim BJ, Patry C, Hoffmann GF, Endlich N, Bracke K, Weiß M, Guse AH, Lassé M, Rinschen M, Braun F, Huber TB, Puelles VG, Schmitt CP, Oh J. Kidney Int. 2022 Mar 7:S0085-2538(22)00175-2.
9.

Podocytes Produce and Secrete Functional Complement C3 and Complement Factor H.
Mühlig AK, Keir LS, Abt JC, Heidelbach HS, Horton R, Welsh GI, Meyer-Schwesinger C, Licht C, Coward RJ, Fester L, Saleem MA, Oh J. Front Immunol. 2020 Aug 14;11:1833. 
10.
Mühlig AK, Lee JY, Kemper MJ, Kronbichler A, Yang JW, Lee JM, Shin JI, Oh J. J Clin Med. 2019 Jun 16;8(6):860. 

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Paul

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  • Mailadresse: Kevin Paul, MD
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  • Datum + Kategorie: Clinician Scientist

Schild

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  • Mailadresse: Raphael-Sebastian Schild, MD
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  • Datum + Kategorie: Post Doc

Schulz-Jürgensen

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  • Mailadresse: Sebastian Schulz-Jürgensen, MD
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  • Datum + Kategorie: Post Doc

Martinistraße 52
Campus Research II N25
20246 Hamburg Germany
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University Medical Center Hamburg - Eppendorf

III. Department of Medicine