Dysregulated mesenchymal PDGFR-β drives kidney fibrosis.

Buhl EM, Djudjaj S, Klinkhammer BM, Ermert K, Puelles VG, Lindenmeyer MT, Cohen CD, He C, Borkham-Kamphorst E, Weiskirchen R, Denecke B, Trairatphisan P, Saez-Rodriguez J, Huber TB, Olson LE, Floege J, Boor P. Dysregulated mesenchymal PDGFR-β drives kidney fibrosis. EMBO Mol Med. 2020 Mar 6;12(3):e11021. doi: 10.15252/emmm.201911021. Epub 2020 Jan 14. PMID: 31943786; PMCID: PMC7059015.

Edenhofer

  • Tags: E
  • Mailadresse: Ilka Edenhofer
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  • Datum + Kategorie: Technician

Efficient renal recruitment of macrophages and T cells in mice lacking the duffy antigen/receptor for chemokines.

Vielhauer V, Allam R, Lindenmeyer MT, Cohen CD, Draganovici D, Mandelbaum J, Eltrich N, Nelson PJ, Anders HJ, Pruenster M, Rot A, Schlöndorff D, Segerer S. Efficient renal recruitment of macrophages and T cells in mice lacking the duffy antigen/receptor for chemokines.Am J Pathol. 2009 Jul;175(1):119-31. doi: 10.2353/ajpath.2009.080590. Epub 2009 Jun 4. PMID: 19498001; PMCID: PMC2708800.

Endothelial-Specific Deletion of CD146 Protects Against Experimental Glomerulonephritis in Mice.

Abed A, Leroyer AS, Kavvadas P, Authier F, Bachelier R, Foucault-Bertaud A, Bardin N, Cohen CD, Lindenmeyer MT, Genest M, Joshkon A, Jourde-Chiche N, Burtey S, Blot-Chabaud M, Dignat-George F, Chadjichristos CE. Endothelial-Specific Deletion of CD146 Protects Against Experimental Glomerulonephritis in Mice.

Hypertension. 2021 Apr;77(4):1260-1272. doi: 10.1161/HYPERTENSIONAHA.119.14176. Epub 2021 Mar 10. PMID: 33689459.

Eur J Clin Invest.

Gerth J, Cohen CD, Hopfer U, Lindenmeyer MT, Sommer M, Gröne HJ, Wolf G. Collagen type VIII expression in human diabetic nephropathy. Eur J Clin Invest.2007 Oct;37(10):767-73. doi: 10.1111/j.1365-2362.2007.01864.x. PMID: 17888087.

Fibronectin is up-regulated in podocytes by mechanical stress.

Kliewe F, Kaling S, Lötzsch H, Artelt N, Schindler M, Rogge H, Schröder S, Scharf C, Amann K, Daniel C, Lindenmeyer MT, Cohen CD, Endlich K, Endlich N. Fibronectin is up-regulated in podocytes by mechanical stress. FASEB J. 2019 Dec;33(12):14450-14460. doi: 10.1096/fj.201900978RR. Epub 2019 Nov 1. PMID: 31675484.

Front Immunol.

Lei Y, Devarapu SK, Motrapu M, Cohen CD, Lindenmeyer MT, Moll S, Kumar SV, Anders HJ. Interleukin-1β Inhibition for Chronic Kidney Disease in Obese Mice With Type 2 Diabetes. Front Immunol. 2019 May 29; 10:1223. doi: 10.3389/fimmu.2019.01223. PMID: 31191559; PMCID: PMC6549251.

Gies

  • Tags: G
  • Mailadresse: Sydney Gies, MD
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  • Datum + Kategorie: CLINICIAN SCIENTIST

Gürler

  • Tags: G
  • Mailadresse: Selin Gürler
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  • Datum + Kategorie: study coordinator

Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors. Amino Acids.

Vuille-dit-Bille RN, Camargo SM, Emmenegger L, Sasse T, Kummer E, Jando J, Hamie QM, Meier CF, Hunziker S, Forras-Kaufmann Z, Kuyumcu S, Fox M, Schwizer W, Fried M, Lindenmeyer M, Götze O, Verrey F. Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors. Amino Acids. 2015 Apr;47(4):693-705. doi: 10.1007/s00726-014-1889-6. Epub 2014 Dec 23. PMID: 25534429.

Human nephrosclerosis triggers a hypoxia-related glomerulopathy. Am J Pathol.

Neusser MA, Lindenmeyer MT, Moll AG, Segerer S, Edenhofer I, Sen K, Stiehl DP, Kretzler M, Gröne HJ, Schlöndorff D, Cohen CD. Human nephrosclerosis triggers a hypoxia-related glomerulopathy. Am J Pathol. 2010 Feb;176(2):594-607. doi: 10.2353/ajpath.2010.090268. Epub 2009 Dec 17. PMID: 20019191; PMCID: PMC2808068.

J Am Soc Nephrol.

Kumar Vr S, Darisipudi MN, Steiger S, Devarapu SK, Tato M, Kukarni OP, Mulay SR, Thomasova D, Popper B, Demleitner J, Zuchtriegel G, Reichel C, Cohen CD, Lindenmeyer MT, Liapis H, Moll S, Reid E, Stitt AW, Schott B, Gruner S, Haap W, Ebeling M, Hartmann G, Anders HJ. Cathepsin S Cleavage of Protease-Activated Receptor-2 on Endothelial Cells Promotes Microvascular Diabetes Complications. J Am Soc Nephrol. 2016 Jun;27(6):1635-49. doi: 10.1681/ASN.2015020208. Epub 2015 Nov 13. PMID: 26567242; PMCID: PMC4884104.

J Am Soc Nephrol.

Sharma K, Karl B, Mathew AV, Gangoiti JA, Wassel CL, Saito R, Pu M, Sharma S, You YH, Wang L, Diamond-Stanic M, Lindenmeyer MT, Forsblom C, Wu W, Ix JH, Ideker T, Kopp JB, Nigam SK, Cohen CD, Groop PH, Barshop BA, Natarajan L, Nyhan WL, Naviaux RK. Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease. J Am Soc Nephrol.2013 Nov;24(11):1901-12. doi: 10.1681/ASN.2013020126. Epub 2013 Oct 10. PMID: 23949796; PMCID: PMC3810086.

J Am Soc Nephrol.

Beeken M, Lindenmeyer MT, Blattner SM, Radón V, Oh J, Meyer TN, Hildebrand D, Schlüter H, Reinicke AT, Knop JH, Vivekanandan-Giri A, Münster S, Sachs M, Wiech T, Pennathur S, Cohen CD, Kretzler M, Stahl RA, Meyer-Schwesinger C. Alterations in the ubiquitin proteasome system in persistent but not reversible proteinuric diseases. J Am Soc Nephrol. 2014 Nov;25(11):2511-25. doi: 10.1681/ASN.2013050522. Epub 2014 Apr 10. PMID: 24722446; PMCID: PMC4214514.

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