The classical pathway triggers pathogenic complement activation in membranous nephropathy

January 2023 | New Publication
Seifert L et al., Nat Commun 2023
This work from the Laboratory of Antigen-Specific Disease Targeting characterizes the complement activation pathways in patients with primary membranous nephropathy and identifies a pathogenic role of the complement system in the first antigen-specific autoimmune model of membranous nephropathy.
 
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Nat Commun - The classical pathway triggers pathogenic complement activation in membranous nephropathy

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