Cell-type-specific damage scores reveal kidney and liver disease trajectories in single-cell and spatial transcriptomics
August 2026 | New Publication
Padvitski T et al., Cell Genom. 2026
The authors introduce a single-cell transcriptomic framework that quantifies progressive cellular damage across degenerative disease models. Applied to kidney and liver injury, the approach reveals conserved damage trajectories, circadian disruption in podocytes, and a hepatocyte damage threshold linked to senescence and metabolic dysfunction.
For further information visit:
Cell-type-specific damage scores reveal kidney and liver disease trajectories in single-cell and spatial transcriptomics
Cell-type-specific damage scores reveal kidney and liver disease trajectories in single-cell and spatial transcriptomics
More articles in this category
Martinistraße 52
Campus Research II N25
20246 Hamburg Germany
Categories
Services
