Podocyte expression of human phospholipase A2 receptor 1 causes immune-mediated membranous nephropathy in mice
February 2023 | New Publication
Tomas NM et al., Kidney Int 2023
This study from the Laboratory for Antigen-Specific Disease Targeting introduces a mouse line expressing the human PLA2R in podocytes, which spontaneously develops membranous nephropathy, representing the first antigen-specific model of PLA2R1-associated membranous nephropathy.
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KI - Podocyte expression of human phospholipase A2 receptor 1 causes immune-mediated membranous nephropathy in mice
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