Our work opens a pathomechanisms-based understanding and future classification of antibody-mediated podocytopathies in both adults and children, voiding the current classification as ‘Idiopathic’ Nephrotic Syndrome in children or disease description based on histological pattern as in Minimal Change Disease or Focal Segmental Glomerulosclerosis in adults. It paves the way for pathomechanisms-based diagnosis, prognostication, and therapeutic approaches in affected patients in the future.
This work was performed at III. Medical Department of Internal Medicine in the groups of Nicola M. Tomas and Tobias B. Huber. It was part of the postdoctoral work of Felicitas E. Hengel within her iPRIME clinician scientist scholarship. All three authors have strong research interests in the field of podocytopathies and autoimmune kidney disease.- Congratulations to all authors!
