Huang

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  • Mailadresse: Ming Huang, PhD
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  • Datum + Kategorie: Post Doc

Jäger

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  • Mailadresse: Julius Jäger
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  • Datum + Kategorie: MD student

Jost

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  • Mailadresse: Elena Jost
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  • Datum + Kategorie: Clinician Scientist

Köhler

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  • Mailadresse: Sybille Köhler, PhD
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  • Datum + Kategorie: Research Group Leader

Sybille Köhler

Laboratory for kidney-driven inter-organ signaling

Mission Statement

“Understanding the functional role of Drosophila nephrocytes as key modulators of fly physiology”

— Sybille Köhler, PhD

Team Members

Research

©Sybille Köhler, created with BioRender

The Drosophila(fruit fly) kidney consists of the Malpighian tubules and nephrocytes, the latter representing the homologue cells to mammalian kidney podocytes, as they share a high similarity in morphology and the molecular make-up of the filtration barrier. One major functional role of nephrocytes is to filter and endocytose factors from the haemolymph (blood). This is crucial for fly physiology in states of health and disease, as Drosophila has an open circulatory system. The group of Dr. Sybille Köhler therefore investigates the role of nephrocytes as key modulators of fly physiology in disease states such as diabetes and during aging. In detail, inter-organ signaling including the cross-talk between nephrocytes and the heart, immune system and gut are investigated. In addition, nephrocytes serve as a great tool to study molecular mechanisms such as mechanosensation and protein function. The findings obtained within the fly model will be translated into the mammalian organism to understand mechanisms during podocyte injury in greater detail.

Sybille Köhler, PhD

Principle Investigator
Research Group Leader

III. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE)
Martinistr. 52
20246 Hamburg, Germany

CV

  • Current Position

    since 2025 Co-speaker iPRIME-PhD EKFS Medical Scientist Programm
    since 2025 Principal Investigator CRC/TRR 422 Project A4
    since 2024 Principal Investigator CRC 1192 Project B3
    since 2022 Principal Investigator STOP-FSGS consortium Project 3
    since 2021 Research Group Leader, III. Department of Medicine (Prof. Tobias Huber), Hamburg, Germany

  • University Training

    2008 - 2011

    Studies in economics, Johannes-Gutenberg-University Mainz, Germany                     
    2005 - 2010 Studies in biology, Johannes-Gutenberg-University Mainz, Germany   

  • Academic qualifications

    2011 - 2016

    PhD student, Department II of Internal Medicine, Nephrolab (Prof. T. Benzing), Cologne                 
    2011 Bachelor thesis, Institute for Management, Johannes-Gutenberg-University Mainz, Germany                     
    2010 Diploma thesis, Department of Pharmacology, University Hospital Mainz (Dr. S. Horke), Mainz, Germany

  • Previous professional career

    Scientific postgraduate education:

    2019 - 2021

    PostDoctoral Fellow, Biomedical Sciences, University of Edinburgh (Dr. Barry Denholm), Scotland, UK
    2016 - 2019

    PostDoc, Department II of Internal Medicine and Center for Molecular Medicine (Prof. P. Brinkkötter), Cologne, Germany

  • Selected awards and honors

    2022 - 2020 Rahel Liebeschütz-Plaut Mentoring Programme, Mentee 
    2022 - 2020

    AJP-Renal Early Career Editorial Fellowship
    2019

    Research fellowship from the Deutsche Forschungsgesellschaft (DFG), Fellow
    2017

    Fritz-Scheler-Stipendium from the German Society of Nephrology
    2017

    NetEX Professorinnenprogramm of the University of Cologne

Selected publications

1.

Elevated Piezo levels cause structural and functional alterations in Drosophila garland nephrocytes. Hazelton-Cavill P, Alornyo KK, Bouchard M, Schulz K, Huber TB, Denholm B, Koehler S.  Life Sci Alliance. 2026 Feb 9;9(4):e202503515. 
2.

Piezo activity levels need to be tightly regulated to maintain normal morphology and function in pericardial nephrocytes. Schulz K, Hazelton-Cavill P, Alornyo KK, Edenhofer I, Lindenmeyer M, Lohr C, Huber TB, Denholm B, Koehler S.  Sci Rep. 2024 Nov 16;14(1):28254. 
3.

The 14th International Podocyte Conference 2023: from podocyte biology to glomerular medicine. Koehler S, Hengel FE, Dumoulin B, Damashek L, Holzman LB, Susztak K, Huber TB; International Podocyte Conference Organizing Committee. Kidney Int. 2024 May;105(5):935-952. 
4.

The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration. Sachs W, Blume L, Loreth D, Schebsdat L, Hatje F, Koehler S, Wedekind U, Sachs M, Zieliniski S, Brand J, Conze C, Florea BI, Heppner F, Krüger E, Rinschen MM, Kretz O, Thünauer R, Meyer-Schwesinger C. T. Nat Commun. 2024 Mar 1;15(1):1897.
5.

A protective role for Drosophila Filamin in nephrocytes via Yorkie mediated hypertrophy.Koehler S, Huber TB, Denholm B. Life Sci Alliance. 2022 Aug 3;5(12):e202101281. 
6.

Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier.
Koehler S, Odenthal J, Ludwig V, Jess DU, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HHH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T, Iden S, Brinkkoetter PT. Kidney Int. 2021 Dec 17:S0085-2538(21)01150-9. doi: 10.1016/j.kint.2021.11.030.
7.

Proteome Analysis of Isolated Podocytes Reveals Stress Responses in Glomerular Sclerosis..
Koehler S, Kuczkowski A, Kuehne L, Jüngst C, Hoehne M, Grahammer F, Eddy S, Kretzler M, Beck BB, Höhfeld J, Schermer B, Benzing T, Brinkkoetter PT, Rinschen MM. J Am Soc Nephrol. 2020 Mar;31(3):544-559.
8.

Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics.
Brinkkoetter PT, Bork T, Salou S, Liang W, Mizi A, Özel C, Koehler S, Hagmann HH, Ising C, Kuczkowski A, Schnyder S, Abed A, Schermer B, Benzing T, Kretz O, Puelles VG, Lagies S, Schlimpert M, Kammerer B, Handschin C, Schell C, Huber TB. Cell Rep. 2019 Apr 30;27(5):1551-1566.e5.
9.

Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes.
Koehler S, Brähler S, Braun F, Hagmann H, Rinschen MM, Späth MR, Höhne M, Wunderlich FT, Schermer B, Benzing T, Brinkkoetter PT. Kidney Int. 2017 Feb 7. pii: S0085-2538(16)30745-1.
10.

A Single and Transient Ca2+ Wave in Podocytes does not induce Changes in Glomerular Filtration and Perfusion.
Koehler S, Brähler S, Binz J, Hackl M, Hagmann H, Kuczkowski A, Vogt M, Wunderlich C, Wunderlich T, Schweda F, Schermer B, Benzing T, Brinkkoetter PT. Sci Rep. 2016 Oct 19;6:35400.
11.

Par3A is dispensable for the function of the glomerular filtration barrier of the kidney.
Koehler S, Tellkamp F, Niessen C, Bloch W, Kerjaschki D, Schermer B, Benzing T, Brinkkoetter PT. Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F112-9.

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Kolck

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  • Mailadresse: Charlotte Kolck
  • Datum + Kategorie: MD student

Komisarenko

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  • Mailadresse: Inga Komisarenko
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  • Datum + Kategorie: study coordinator

Kretz

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  • Mailadresse: Oliver Kretz, MD
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  • Datum + Kategorie: Head of Electron Microscopy Facility

Oliver Kretz

Laboratory for structural biology of the kidney

Mission Statement

“Understanding the mechanisms of kidney aging and the relevance of interorgan signaling in this process”

— Oliver Kretz, MD

Team Members

Research

Many of the phenotypes in human kidney disease are only detectable at the ultrastructural level. This holds also true for the model systems of genetic and epigenetic based disturbances of renal development, biology or aging. Our group applies transmission and scanning microscope techniques in human and animal tissue (e.g. mouse, rat, zebrafish, drosophila) in order to detect and characterize subtle ultrastructural alterations e.g. of the glomerular filtration barrier, the actin cytoskeleton or intracellular vesicle formation and trafficking at a qualitative and quantitative level.

Moreover, our thematic focus deals with the understanding of mechanisms underlying kidney aging which is an issue of growing relevance in the aging population of western countries. To this end we make use of the progeroid Ercc1Δ/- mutant mouse line as an experimental platform for studies into aging. It harbors attenuated Excision repair cross-complementation 1 activity, a key component of several DNA repair pathways. In this model system we apply different conditions which we and others have recently shown to have beneficial effects on aging like modulation of the activin/myostatin pathway or dietary restriction. By deep morphological, functional and molecular (single nuclei transcriptomics) analysis we aim to identify pathways involved in aging in different cell types of the kidney and in other organs like muscle, liver or CNS. Finally, we have a special interest in the concept of inter-organ communication during aging that is now emerging. We hope to identify kidney derived factors influencing the aging of other organ systems and vice versa.

Oliver Kretz, MD

III. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE)
Martinistr. 52
20246 Hamburg, Germany

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CV

  • Current Position

    since 2025

    Co-Director Core Facility for Electron Microscopy, UKE & Center for Molecular Neurobiology Hamburg

    since 2017

    Laboratory head, Electron microscopy facility, III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Prof. Dr. Tobias B. Huber

  • University Training

    1987 - 1994

    Study of Medicine, University Saarbrücken, Germany; University Rennes (F); University Vienna (A) and University Kiel, Germany (final exam: sehr gut)

    2006 - 2010

    Master of Health Business Administration, University Erlangen-Nürnberg, Germany

  • Academic qualifications

    2006

    Habilitation in “Anatomy and cell biology” at the University of Freiburg (“Steroid hormone signaling in the CNS”)

    1998

    MD at the University of Saarbrücken („Regulation of the hypothalamo-pituitary-adrenal axis in glucocorticoid receptor knockout mice “ -  magna cum laude)

  • Previous professional career

    Scientific postgraduate education:

    2014 - 2017

    Laboratory head, Electron microscopy facility, IV. Medical Clinic, University Medical Center Freiburg, Prof. Dr. Tobias B. Huber

    2013 - 2014

    Senior Scientist, BIOSS Cluster of Excellence, University  Freiburg, Germany

    2009 - 2013

    Group leader and Senior scientist at the Division of Neuroanatomy (Chair: Prof. Dr. M. Frotscher)

    2001 - 2007

    Postdoctoral fellow, Department of Anatomy and cell biology, University Freiburg (Prof. Dr. M. Frotscher)

    1999 - 2001

    Postdoctoral fellow, Division Molecular Biology of the Cell I, German Cancer Research Center, Heidelberg (Chair. Prof. Dr. G. Schütz)

    1995 - 1998

    Postdoctoral fellow, Department of Anatomy, Neuroanatomical Division, University Saarbrücken

  • Selected awards and honors

    2001

    EMBO short term fellow

    1999 - 2001

    DFG research fellow

    1999

    Young Investigator Award of the University Saarbrücken

Selected publications

1.
Rogg M, Weißer L, Maier JI, Sigle A, Helmstädter M, Stigler M, Sammarco A, Gräwe K, Andreev G, Kark C, Ramakrishnan SK, Özel C, Butt L, Arnold F, Bechtel-Walz W, Schilling O, Tanriver Y, Brinkkötter P, Grabbert M, Simons M, Werner M, Kretz O, Benzing T, Huber TB, Schell C. Sci Adv. 2025 Nov 28;11(48):eady1623. 
2.
Zahner G, Dehde S, Seifert L, Huang M, Kretz O, Huber TB, Tomas NM.  Kidney Int. 2025 Dec;108(6):1179-1183. 
3.
Czogalla J, Hausmann F, Lagies S, Gies SE, Christiansen S, Kaiser N, Haas F, Okabayashi Y, Kylies D, Hofmann S, Franzin R, Sabra N, Bouari S, Fang Y, Ambagtsheer G, Edenhofer I, Chilla S, Mühlig AK, Zimmermann M, Wong MN, Yokoo T, Kretz O, Lindenmeyer M, Grahammer F, Hoogduijn MJ, de Bruin R, Kuehl M, Hänzelmann S, Kammerer B, Gesualdo L, Bonn S, Minnee RC, Huber TB, Puelles VG.  JCI Insight. 2025 Sep 23;10(18):e190185. 
4.
Kuehl M, Okabayashi Y, Wong MN, Gernhold L, Gut G, Kaiser N, Schwerk M, Gräfe SK, Ma FY, Tanevski J, Schäfer PSL, Mezher S, Sarabia Del Castillo J, Goldbeck-Strieder T, Zolotareva O, Hartung M, Delgado Chaves FM, Klinkert L, Gnirck AC, Spehr M, Fleck D, Joodaki M, Parra V, Shaigan M, Diebold M, Prinz M, Kranz J, Kux JM, Braun F, Kretz O, Wu H, Grahammer F, Heins S, Zimmermann M, Haas F, Kylies D, Wanner N, Czogalla J, Dumoulin B, Zolotarev N, Lindenmeyer M, Karlson P, Nyengaard JR, Sebode M, Weidemann S, Wiech T, Groene HJ, Tomas NM, Meyer-Schwesinger C, Kuppe C, Kramann R, Karras A, Bruneval P, Tharaux PL, Pastene D, Yard B, Schaub JA, McCown PJ, Pyle L, Choi YJ, Yokoo T, Baumbach J, Sáez PJ, Costa I, Turner JE, Hodgin JB, Saez-Rodriguez J, Huber TB, Bjornstad P, Kretzler M, Lenoir O, Nikolic-Paterson DJ, Pelkmans L, Bonn S, Puelles VG. Nature. 2025 Jul 18. doi: 10.1038/s41586-025-09225-2. 
5.
Hengel FE, Dehde S, Kretz O, Engesser J, Zimmermann T, Huber TB, Tomas NM. J Clin Invest. 2025 Jan 16;135(5):e186769. 
6.
Vermeij WP, Alyodawi K, van Galen I, von der Heide JL, Birkisdóttir MB, Van't Sant LJ, Ozinga RA, Komninos DSJ, Smit K, Rijksen YMA, Brandt RMC, Barnhoorn S, Jaarsma D, Vaiyapuri S, Ritvos O, Huber TB, Kretz O, Patel K. J Cachexia Sarcopenia Muscle. 2024 Dec;15(6):2361-2374. 
7.
Hengel FE, Dehde S, Lassé M, Zahner G, Seifert L, Schnarre A, Kretz O, Demir F, Pinnschmidt HO, Grahammer F, Lucas R, Mehner LM, Zimmermann T, Billing AM, Oh J, Mitrotti A, Pontrelli P, Debiec H, Dossier C, Colucci M, Emma F, Smoyer WE, Weins A, Schaefer F, Alachkar N, Diemert A, Hogan J, Hoxha E, Wiech T, Rinschen MM, Ronco P, Vivarelli M, Gesualdo L, Tomas NM, Huber TB; International Society of Glomerular Disease. N Engl J Med. 2024 Aug 1;391(5):422-433. 
8.
Tresse E, Marturia-Navarro J, Sew WQG, Cisquella-Serra M, Jaberi E, Riera-Ponsati L, Fauerby N, Hu E, Kretz O, Aznar S, Issazadeh-Navikas S. Mol Psychiatry. 2023 Nov;28(11):4902-4914. 
9.
Kylies D, Zimmermann M, Haas F, Schwerk M, Kuehl M, Brehler M, Czogalla J, Hernandez LC, Konczalla L, Okabayashi Y, Menzel J, Edenhofer I, Mezher S, Aypek H, Dumoulin B, Wu H, Hofmann S, Kretz O, Wanner N, Tomas NM, Krasemann S, Glatzel M, Kuppe C, Kramann R, Banjanin B, Schneider RK, Urbschat C, Arck P, Gagliani N, van Zandvoort M, Wiech T, Grahammer F, Sáez PJ, Wong MN, Bonn S, Huber TB, Puelles VG. Nat Nanotechnol. 2023 Apr;18(4):336-342. 
10.
Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC.  Cell. 2020 May 28;181(5):1080-1096.e19. 
11.
Klein Geltink RI, O'Sullivan D, Corrado M, Bremser A, Buck MD, Buescher JM, Firat E, Zhu X, Niedermann G, Caputa G, Kelly B, Warthorst U, Rensing-Ehl A, Kyle RL, Vandersarren L, Curtis JD, Patterson AE, Lawless S, Grzes K, Qiu J, Sanin DE, Kretz O, Huber TB, Janssens S, Lambrecht BN, Rambold AS, Pearce EJ, Pearce EL. Cell.2017 Oct 5;171(2):385-397.e11.
12.
Chatterjee A, Seyfferth J, Lucci J, Gilsbach R, Preissl S, Böttinger L, Mårtensson CU, Panhale A, Stehle T, Kretz O, Sahyoun AH, Avilov S, Eimer S, Hein L, Pfanner N, Becker T, Akhtar A. Cell.2016 Oct 20;167(3):722-738.e23.
13.
Buck MD, O'Sullivan D, Klein Geltink RI, Curtis JD, Chang CH, Sanin DE, Qiu J, Kretz O, Braas D, van der Windt GJ, Chen Q, Huang SC, O'Neill CM, Edelson BT, Pearce EJ, Sesaki H, Huber TB, Rambold AS, Pearce EL. Cell. 2016 Jun 30;166(1):63-76.

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Kuhr

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  • Mailadresse: Eva-Maria Kuhr
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  • Datum + Kategorie: Technician

Kummerer

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  • Mailadresse: Antonia Kummerer
  • Datum + Kategorie: MD student

Kylies

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  • Mailadresse: Dominik Kylies, MD
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  • Datum + Kategorie: Clinician Scientist

Laufer

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  • Mailadresse: Sandra Laufer, PhD
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  • Datum + Kategorie: Post Doc

Le

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  • Mailadresse: Dinh To Le, PhD
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  • Datum + Kategorie: Post Doc

Liagos

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  • Mailadresse: Samaneh Liagos
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  • Datum + Kategorie: study coordinator

Lindenmeyer

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  • Mailadresse: Maja Lindenmeyer, PhD
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  • Datum + Kategorie: LABORATORY HEAD/HEAD OF BIOBANK

Maja Lindenmeyer

Biobanking Study group

Mission Statement

“Facilitate translational renal research and provide a valuable source to accelerate the development of better patient diagnostics and therapies – only together we can make a difference”

— Maja Lindenmeyer, PhD

Team Members

Research

©Maja Lindenmeyer, created with BioRender

Our group represents the core facility of the “European Renal cDNA Bank-Kroener Fresenius Biopsy Bank” (ERCB-KFB), a multicenter study for gene expression analysis in different human renal diseases, and the “Hamburg and European Renal Omics Bank” (HERO), a collaborative project for conducting translational research in human renal diseases. Using state of the art omics and non-omics technologies, we aim to

  1. support the renal scientific community by translational research
  2. expand our knowledge of disease pathomechanisms
  3. define molecular disease subgroups
  4. identify biomarkers
  5. find new ways treating human renal diseases.

Maja Lindenmeyer, PhD

III. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE)
Martinistr. 52
20246 Hamburg, Germany

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CV

  • Current Position

    since 2025 Principal Investigator CRC/TRR 422 Project CP3 
    since 2024 Principal Investigator CRC 1192 
    since 2022 Principal Investigator / Co-Coordinator BMBF STOP-FSGS
    since 2022

    Principal Investigator BMBF UPTAKE
    since 2021

    Project Leader/ Study Coordinator of the Hamburg and European Renal Omics Biobank (HERO)
    since 2018

    Laboratory head, III. Department of Medicine, UKE, Prof. Dr. T. B. Huber
    since 2018 Coordinator of the ERCB

  • University Training

    1994 – 2000

    Chemistry, Technical University Karlsruhe, University of Freiburg

  • Academic qualifications

    2014 - 2020

    Habilitation in Molecular Nephrology, University of Zurich (Switzerland)
    2004

    PhD, Department of Pharmaceutical Biology and Biotechnology, University of Freiburg
    2000

    Diploma in Chemistry, University of Freiburg

  • Previous professional career

    2015 – 2018

    Junior Group leader, Nephrology Center, IV. Department of Medicine, University Hospital of Munich (LMU)
    2012 – 2018

    Deputy-Coordinator of the European Renal cDNA Bank-Kroener Fresenius
    Biobank (ERCB)
    2010 – 2014

    Laboratory Head of the Nephrology Lab Zurich, University of Zurich (Switzerland)
    2008 – 2010

    Postdoctoral Fellow, Institute of Physiology and Division of Nephrology, University of Zurich (Switzerland), Prof. Dr. C. Cohen
    2006 – 2007

    Postdoctoral Fellow, Nephrology Center, IV. Deparment of Medicine, University Hospital of Munich (LMU), Prof Dr. C. Cohen
    2004 – 2005

    Postdoctoral Fellow, School of Biological Sciences, Queen Mary College, London (UK), Prof. Dr. M. Warren

  • Selected awards and honors

    2010 - 2020

    Habilitation Scholarship of the Holcim Foundation
    2004 – 2005

    Post-Doc fellowship of the German Academic Exchange Service (DAAD)
    2001 – 2003

    PhD fellowship of the “Landesgraduiertenförderung Baden-Württemberg”

Selected publications

1.

Molecular consequences of SARS-CoV-2 liver tropism.
Wanner N*, Andrieux G*, Badia-i-Mompel P, Edler C, Pfefferle S, Lindenmeyer M, Schmidt-Lauber C, Czogalla J, Wong MN, Okabayashi Y, Braun F, Lütgehetmann M, Meister E, Lu S, Noriega MLM, Günther T, Grundhoff A, Fischer N, Bräuninger H, Lindner D, Westermann D, Haas F, Roedl K, Kluge S, Addo MM, Huber S, Lohse AW, Reiser J, Ondruschka B, Sperhake JP, Saez-Rodriguez J, Boerries M, Hayek SS, Aepfelbacher M, Scaturro P*, Puelles VG*, Huber TB*. Nat Metab 2022 Mar;4(3):310-319
2.

Pro-cachectic factors link experimental and human chronic kidney disease to skeletal muscle wasting.
Solagna F, Tezze C, Lindenmeyer MT, Lu S, Wu G, Liu S, Zhao Y, Mitchell R, Meyer C, Omairi S, KilicT, Paolini A, Ritvos O, Pasternack A, Matsakas A, Kylies D, Wiesch JS zur, Turner J-E, Wanner N, Nair V, Eichinger F, Menon R, Martin I V., Klinkhammer BM, Hoxha E, Cohen CD, Tharaux P-L, Boor P, Ostendorf T, Kretzler M, Sandri M, Kretz O, Puelles VG*, Patel K*, Huber TB*, J Clin Invest. 2021 Jun 1;131(11).
3.

Endothelial-Specific Deletion of CD146 Protects Against Experimental Glomerulonephritis in Mice.
Abed A*, Leroyer AS*, Kavvadas P*, Authier F, Bachelier R, Foucault-Bertaud A, Bardin N, Cohen CD, Lindenmeyer MT, Genest M, Joshkon A, Jourde-Chiche N, Burtey S, Blot-Chabaud M, Dignat-George F*, Chadjichristos CE*. Hypertension. 2021 Apr;77(4):1260-1272
4.

SARS-CoV-2 renal tropism associates with acute kidney injury.
Braun F, Lütgehetmann M, Pfefferle S, Wong MN, Carsten A, Lindenmeyer MT, Nörz D, Heinrich F, Meißner K, Wichmann D, Kluge S, Gross O, Pueschel K, Schröder AS, Edler C, Aepfelbacher M, Puelles VG, Huber TB. Lancet. 2020 Aug;396(10251):597–8.
5.

ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage.
Sachs M, Wetzel S, Reichelt J, Sachs W, Schebsdat L, Zielinski S, Seipold L, Heintz L, Müller SA, Kretz O, Lindenmeyer M, Wiech T, Huber TB, Lüllmann-Rauch R, Lichtenthaler SF, Saftig P, Meyer-Schwesinger C. J Am Soc Nephrol. 2021 Jun 1;32(6):1389-1408
6.

Dysregulated mesenchymal PDGFR-β drives kidney fibrosis
Buhl EM, Djudjaj S, Klinkhammer BM, Ermert K, Puelles VG, Lindenmeyer MT, Cohen CD, He C, Borkham-Kamphorst E, Weiskirchen R, Denecke B, Trairatphisan P, Saez-Rodriguez J, Huber TB, Olson LE, Floege J, Boor P. EMBO Mol Med. 2020 Mar 6;12(3):e11021
7.

Multiorgan and Renal Tropism of SARS-CoV-2.
Puelles VG*, Lütgehetmann M*,Lindenmeyer MT*, Sperhake JP*, Wong MN, Allweiss L,Chilla S, Heinemann A, Wanner N, Liu S, Braun F, Lu S, Pfefferle S, Schröder AS, Edler C,Gross O, Glatzel M, Wichmann D, Wiech T, Kluge S, Pueschel K, Aepfelbacher M, Huber TB.N Engl J Med. 2020 Aug 6;383(6):590–2.
8.

Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution.
Rajaram RD, Dissard R, Faivre A, Ino F, Delitsikou V, Jaquet V, Cagarelli T,Lindenmeyer M,Jansen-Duerr P, Cohen C, Moll S, de Seigneux S.Redox Biol. 2019 Sep;26:101234
9.

Metabolic pathways and immunometabolism in rare kidney diseases.
Grayson PC, Eddy S, Taroni JN, Lightfoot YL, Mariani L, Parikh H, Lindenmeyer MT, Ju W, Greene CS, Godfrey B, Cohen CD, Krischer J, Kretzler M, Merkel PA; Vasculitis Clinical Research Consortium, the European Renal cDNA Bank cohort, and the Nephrotic Syndrome Study Network. Ann Rheum Dis. 2018 Aug;77(8):1226-1233.
10.

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts.
Shved N, Warsow G, Eichinger F, Hoogewijs D, Brandt S, Wild P, Kretzler M, Cohen CD,Lindenmeyer MT.Sci Rep. 2017 Aug 17;7(1):8576.

*contributed equally

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